Research on plasma modification of chitosan film surface by plasma cleaner manufacturers:

Chitosan is a natural polycationic biopolysaccharide produced by the deacetylation reaction of chitin. It has excellent biocompatibility, biodegradability, safety and non-toxicity, and has broad application prospects in tissue engineering. , Such as artificial skin, cartilage tissue engineering scaffold, drug controlled release carrier, artificial liver, etc.
Chitosan and its derivatives have also attracted attention as a good scaffold material for corneal tissue engineering due to its excellent fiber-forming, membrane-forming properties, permeability, moisture absorption and moisture retention, and certain antibacterial properties. However, due to the strong intramolecular and intermolecular hydrogen bonds, the hydrophilicity is relatively poor, which limits its wider application. Therefore, how to improve the hydrophilicity and biocompatibility is the focus of current research. Fengzhi plasma cleaning machine manufacturer will explain the application of plasma in its treatment.
The surface properties of scaffold materials play an extremely important role in the cell affinity of the materials, and surface modification is a direct and effective way to improve the surface properties of biomaterials. The surface of the scaffold material with hydrophilic groups is beneficial to improve its cell adhesion. Plasma treatment technology is a very effective technology to change the surface properties of materials. Through radio frequency discharge under a certain gas, specific polar groups can be introduced on the surface of the material, thereby improving the hydrophilicity of the material.
Compared with other methods, the plasma surface modification of Chengfeng Zhizhi plasma cleaning machine manufacturer has simple process, simple operation, easy control, low equipment cost, no pollution, does not affect the properties of the matrix material, and has a strong sterilization and disinfection effect. And other advantages, is one of the effective means of surface modification of biological materials. After the chitosan film was treated with plasma, the contact angle was significantly reduced. It shows that after plasma treatment, the polarity of the chitosan film surface increases, and the hydrophilicity increases. This is due to the breakage of bonds on the chitosan film surface and the formation of new hydrophilic groups.
After the plasma cleaning machine manufacturer uses plasma to treat it, the surface morphology of the chitosan film becomes relatively flat, which may be caused by the etching effect of the plasma. There are two mechanisms of etching: one is the sputter etching caused by the impact of energetic particles such as electrons and ions in the plasma on the surface of the material. The second is chemical etching caused by the reaction of radicals in the plasma with certain groups on the surface of the material to generate volatile substances.
When the surface of the glycan film is etched, due to the different etching speeds of different parts, the surface roughness will be changed, accompanied by bond breakage, which can improve its adhesion and moisture absorption properties. The surface of chitosan membrane was modified by nitrogen plasma, and the surface hydrophilicity was improved to a large extent by introducing polar groups such as >C=O (COOR, COOH or CONH). It can be seen that nitrogen plasma surface treatment technology is an effective means to improve the surface hydrophilicity of chitosan.